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Peptide record

TPDB05002

Antibacterial Anticancer Antifungal Antiparasitic standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05002
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLNTFKDWAISIAKGAGKGVLTTLSCKLDKSC
Physicochemical Analysis
C153H256N40O45S2
REQHMPY
LK
3440.08
9.65
5
2
13
+3
1.36
0.255
100.61
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
163.51
9
Residue Composition
number
3
A
0
R
1
N
2
D
2
C
0
E
0
Q
4
G
0
H
2
I
5
L
5
K
0
M
1
F
0
P
3
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 5 K: 5 M: 0 F: 1 P: 0 S: 3 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
33
C153H256N40O45S2
3440.08
9.65
+3
1.36
0.255
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes CO
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

M. luteus ATCC934

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MI
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

dbAMP DRAMP

Other

IC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

dbAMP DRAMP

Other

6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

P.aeruginosa PAO1

Source & Reference

dbAMP DRAMP

Other

TCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025
Evidence 7 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes CO
Evidence 8 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100
Evidence 9 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

M. luteus ATCC934

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MI
Evidence 10 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

dbAMP DRAMP Antifungipept

Other

IC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/
Evidence 11 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

dbAMP DRAMP Antifungipept

Other

6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025
Evidence 12 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

P.aeruginosa PAO1

Source & Reference

dbAMP DRAMP Antifungipept

Other

TCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025
Evidence 13 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes CO
Evidence 14 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100
Evidence 15 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

M. luteus ATCC934

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MI
Evidence 16 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

DRAMP

Other

IC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/
Evidence 17 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

DRAMP

Other

6633 (MIC 12.5 ug/ml), M. luteus ATCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025
Evidence 18 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

P.aeruginosa PAO1

Source & Reference

DRAMP

Other

TCC934 (MIC 25 ug/ml), S. pyogenes COOK (MIC 50 ug/ml), E. coli NIHJ (MIC 100 ug/ml), and P.aeruginosa PAO1 (MIC >100 ug/ml). Updated 7/2019 9/2025