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Peptide record

TPDB04989

Antibacterial Anticancer Antifungal Antiparasitic standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB04989
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifungipept CAFPdb
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AGRGKQGGKVRAKAKTRSSRAGLQFPVGRVHRLLRKGNY
Physicochemical Analysis
C184H318N70O47
DCEIMW
RG
4262.99
12.81
13
0
12
+12
9.86
-0.992
62.56
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
34.95
7
Residue Composition
number
4
A
7
R
1
N
0
D
0
C
0
E
2
Q
7
G
1
H
0
I
3
L
5
K
0
M
1
F
1
P
2
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 4 R: 7 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 7 H: 1 I: 0 L: 3 K: 5 M: 0 F: 1 P: 1 S: 2 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
39
C184H318N70O47
4262.99
12.81
+12
9.86
-0.992
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
This histone-derived peptide is active against Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

P. putida

Source & Reference

dbAMP DRAMP

Other

st Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

(MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoforma
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

ns (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 u
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP

Other

himurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
This histone-derived peptide is active against Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8
Evidence 7 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

P. putida

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

st Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8
Evidence 8 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoforma
Evidence 9 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ns (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 u
Evidence 10 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

himurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
This histone-derived peptide is active against Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8
Evidence 12 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

P. putida

Source & Reference

DRAMP

Other

st Gram+ bacteria B. subtilis, S. aureus (MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8
Evidence 13 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

(MIC 4 ug/ml), S. mutans (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoforma
Evidence 14 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

S. typhimurium

Source & Reference

DRAMP

Other

ns (MIC 8), S. pneumoniae, P. putida (MIC 4 ug/ml), Gram- bacteria E. coli (MIC 8 ug/ml), S. typhimurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 u
Evidence 15 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

S. cerevisiae

Source & Reference

DRAMP

Other

himurium (MIC 4 ug/ml), Serratia sp. (MIC 8 ug/ml), fungi C. albicans, C. neoformans, and S. cerevisiae (MIC 4 ug/ml).