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Peptide record

TPDB04981

Antibacterial Antifungal Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB04981
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
LDVKKIICVACKIKPNPACKKICPK
Physicochemical Analysis
C123H221N33O29S4
REQGHMFSTWY
K
2754.55
9.92
7
1
9
+6
6.97
0.188
109.20
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
250
9.08
5
Residue Composition
number
2
A
0
R
1
N
1
D
4
C
0
E
0
Q
0
G
0
H
4
I
1
L
7
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 4 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 1 K: 7 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C123H221N33O29S4
2754.55
9.92
+6
6.97
0.188
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Panurgines, novel antimicrobial peptides from the venom of communal bee Panurgus calcaratus (Hymenoptera: Andrenidae). | Amino Acids | 2013
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.