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Peptide record

TPDB04968

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB04968
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbACP Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbACP, and other sources, with an available 3D structural model.
Sequence
LLGMIPVAITAISALSKL
Physicochemical Analysis
C84H151N19O22S1
RNDCEQHFWY
L
1811.30
10.10
1
0
12
+1
-1.99
1.778
184.44
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
1
K
1
M
0
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 1 M: 1 F: 0 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C84H151N19O22S1
1811.30
10.10
+1
-1.99
1.778
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. epidermidis (MIC 50 uM). Updated 7/2018 7/2021 6/2026
Evidence 2 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. epidermidis (MIC 50 uM). Updated 7/2018 7/2021 6/2026
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
1.814E6 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 1.814E6 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Targeted Modification of a Novel Amphibian Antimicrobial Peptide from Phyllomedusa tarsius to Enhance Its Activity against MRSA and Microbial Biofilm. | Front Microbiol | 2017
Evidence 4 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.