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Peptide record

TPDB04966

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Quorum sensing Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB04966
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Quorum sensing Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept dbAMP dbAMP 3.0 AI4AVP DRAMP DRAVP 2.0 EnsembleQS QSPred-FL ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
CLGVGSCNDFAGCGYAIVCFW
Physicochemical Analysis
C97H137N23O27S4
REQHKMPT
CG
2185.53
3.10
0
1
10
-1
-5.26
1.157
74.29
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7240
331.27
7
Residue Composition
number
2
A
0
R
1
N
1
D
4
C
0
E
0
Q
4
G
0
H
1
I
1
L
0
K
0
M
2
F
0
P
1
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 4 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 1 K: 0 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
21
C97H137N23O27S4
2185.53
3.10
-1
-5.26
1.157
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>500 µg/mL
Cytotoxic
50% Cytotoxicity | >500 | µg/mL | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Siamycins I and II, new anti-HIV peptides: I. Fermentation, isolation, biological activity and initial characterization. | J Antibiot (Tokyo) | 1995