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Peptide record

TPDB04963

Tachykinin-related peptide 1 Antibacterial Antifungal Neuropeptide Toxicity standard

9 amino acids

3D PDB MODEL

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TPDB ID TPDB04963

Peptide_Name

Tachykinin-related peptide 1

Activity

Antibacterial Antifungal Neuropeptide Toxicity

Activity_category_statistics

Anti-infective peptides Toxicity and safety peptides Neuroactive peptides

Database_Source

AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0

Sequence_Type

standard

Has_Modification No

Description A 9-aa standard natural multi-activity (Antibacterial, Antifungal, Neuropeptide, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.

Sequence

GPSGFLGMR

FASTA

>TPDB04963|Antibacterial;Antifungal;Neuropeptide;Toxicity|length=9
GPSGFLGMR

Formula C40H64N12O11S1

Absent Amino Acids ANDCEQHIKTWYV

Common Amino Acids G

Mass 921.08

PI 11.05

Basic Residues 1

Acidic Residues 0

Hydrophobic Residues 3

Net Charge +1

Boman Index -0.50

Hydrophobicity 0.044

Aliphatic Index 43.33

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 1

number

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 1 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0

Length

Formula

C40H64N12O11S1

Mass

921.08

11.05

Database Source NA

Source NeuroPepV2

Other

Organism Source Pyrrhocoris apterus

Family Tachykinin

Evidence 8 Activity

Activity

Activity Endpoint 0.9% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 300 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

0.9% Hemolysis | 300 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Two Tachykinin-Related Peptides with Antimicrobial Activity Isolated from Triatoma infestans Hemolymph | Microbiology Insights | 2020

Evidence 9 Activity

Activity

Activity Endpoint 16% Killing

Detail Source Activity Toxicity

Activity Measurement 1000 µM

Toxicity Type Cytotoxic

Toxicity Raw

16% Killing | 1000 | µM | target cell: Vero cells

Target

Target Cell Vero cells

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Two Tachykinin-Related Peptides with Antimicrobial Activity Isolated from Triatoma infestans Hemolymph | Microbiology Insights | 2020

Family

Tachykinin