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Peptide record

TPDB04955

Antibacterial Antiviral Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB04955
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
FAVAVKAVAVKAVAVKAVKKAVKKVKKAVKKAVKKKK
Physicochemical Analysis
C184H340N52O38
RNDCEQGHILMPSTWY
K
3889.05
11.65
15
0
22
+15
12.79
0.230
113.24
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
10
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
15
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
11
V
Amino Acid Distribution
A: 10 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 15 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 11
Chemical Descriptors
37
C184H340N52O38
3889.05
11.65
+15
12.79
0.230
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
9.20 µM
Cytotoxic
50% Cytotoxicity | 9.20 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.12208971]CrFK cell:TC50=9.20 µM.

Source & Reference

NA
DRAMP
J Virol. 2002 Oct 76(19):9952-61.