Peptide record

TPDB04950

Antibacterial Anticancer Antifungal Antiparasitic standard
45 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04950
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
RTCENLADKYRGPCFSGCDTHCTTKENAVSGRCRDDFRCWCTKRC
Physicochemical Analysis
C210H331N71O68S8
QIM
C
5194.85
8.10
10
6
8
+3
12.23
-0.951
19.56
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7490
144.18
18
Residue Composition
number
2
A
6
R
2
N
4
D
8
C
2
E
0
Q
3
G
1
H
0
I
1
L
3
K
0
M
2
F
1
P
2
S
5
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 6 N: 2 D: 4 C: 8 E: 2 Q: 0 G: 3 H: 1 I: 0 L: 1 K: 3 M: 0 F: 2 P: 1 S: 2 T: 5 W: 1 Y: 1 V: 1
Chemical Descriptors
45
C210H331N71O68S8
5194.85
8.10
+3
12.23
-0.951
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Inhibited V. dahliae (IC50 5 ug/ml, MIC 15 ug/ml). Also inhibited the growth of a filamentous fungi, F. graminearum, A. solani. and F. culmorum at micromolar concentrations.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Inhibited V. dahliae (IC50 5 ug/ml, MIC 15 ug/ml). Also inhibited the growth of a filamentous fungi, F. graminearum, A. solani. and F. culmorum at micromolar concentrations.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

Inhibited V. dahliae (IC50 5 ug/ml, MIC 15 ug/ml). Also inhibited the growth of a filamentous fungi, F. graminearum, A. solani. and F. culmorum at micromolar concentrations.