Peptide record

TPDB04949

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB04949
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIGALSAKGALKGLAKGLAEHFAN
Physicochemical Analysis
C103H172N30O29
RDCQMPTWYV
A
2294.68
10.32
4
1
12
+2
1.85
0.358
106.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
6
A
0
R
1
N
0
D
0
C
1
E
0
Q
5
G
1
H
1
I
4
L
3
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 1 L: 4 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C103H172N30O29
2294.68
10.32
+2
1.85
0.358
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.8223491] The lethal concentration (LC, the lowest concentration that inhibits growth) was over 50 µM

Source & Reference

APD_complete APD_hemolytic
DRAMP4
Monatsh. Chem. 1970 101:182-189.##EMBO J. 1993 12:4829-4832.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.8223491] The lethal concentration (LC, the lowest concentration that inhibits growth) was over 50 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Monatsh. Chem. 1970 101:182-189.##EMBO J. 1993 12:4829-4832.
Evidence 3 Hemolysis

Activity

[Ref.8223491] The lethal concentration (LC, the lowest concentration that inhibits growth) was over 50 µM
Hemolysis

Source & Reference

APD_complete APD_hemolytic
Monatsh. Chem. 1970 101:182-189.##EMBO J. 1993 12:4829-4832.
DRAMP4
APD_complete APD_hemolytic