Back to search

Peptide record

TPDB04927

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04927
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC
Physicochemical Analysis
C169H295N45O48S3
RDHPSWY
K
3821.65
9.98
6
2
16
+4
5.24
0.357
105.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.27
8
Residue Composition
number
5
A
0
R
1
N
0
D
2
C
2
E
1
Q
5
G
0
H
3
I
5
L
6
K
1
M
1
F
0
P
0
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 2 E: 2 Q: 1 G: 5 H: 0 I: 3 L: 5 K: 6 M: 1 F: 1 P: 0 S: 0 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C169H295N45O48S3
3821.65
9.98
+4
5.24
0.357
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 12.5 uM), S. aureus NCTC 8325 (MIC 50 uM), and C.albicans ATCC 90028 (MIC > 100 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami. | Peptides | 2006
Evidence 8 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.