TPDB04906

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E.

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevi

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 150 µg/mL

Target

Target Organism P.putida

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. a

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 150 µg/mL

Target

Target Organism P.aeruginosa

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

l), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 11 Activity

Activity

Activity Endpoint IC50

Activity Raw

IC50=6.49 µg/ml

Detail Source Activity Anticancer

Activity Measurement 6.49 µg/mL

Target

Cancer Type Lung Cancer

Cell Line A-549

Tissue Affected Lung

Assay & Model

Assay MTT/MTS assay

Testing Time 96-h

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 2003

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.

Evidence 12 Activity

Activity

Activity Endpoint IC50

Activity Raw

IC50=5.62 µg/ml

Detail Source Activity Anticancer

Activity Measurement 5.62 µg/mL

Target

Cancer Type Renal Cancer

Cell Line 293

Tissue Affected Renal

Assay & Model

Assay MTT/MTS assay

Testing Time 96-h

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 2003

Evidence 13 Activity

Activity

Activity Endpoint IC50

Activity Raw

IC50=5.75 µg/ml

Detail Source Activity Anticancer

Activity Measurement 5.75 µg/mL

Target

Cancer Type Renal Cancer

Cell Line 293

Tissue Affected Renal

Assay & Model

Assay MTT/MTS assay

Testing Time 96-h

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 2003

Evidence 14 Activity

Activity

Activity Endpoint IC50

Activity Raw

IC50=4.91 µg/ml

Detail Source Activity Anticancer

Activity Measurement 4.91 µg/mL

Target

Cancer Type Liver Cancer

Cell Line Hep3B

Tissue Affected Liver

Assay & Model

Assay MTT/MTS assay

Testing Time 96-h

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 2003

Evidence 15 Activity

Activity

Activity Endpoint IC50

Activity Raw

IC50=4.88 µg/ml

Detail Source Activity Anticancer

Activity Measurement 4.88 µg/mL

Target

Cancer Type Breast Cancer

Cell Line MCF-7

Tissue Affected Breast

Assay & Model

Assay MTT/MTS assay

Testing Time 96-h

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 2003

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E.

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevi

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 150 µg/mL

Target

Target Organism P.putida

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. a

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 150 µg/mL

Target

Target Organism P.aeruginosa

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

l), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E.

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevi

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 150 µg/mL

Target

Target Organism P.putida

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. a

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 150 µg/mL

Target

Target Organism P.aeruginosa

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

l), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 100 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiviral	DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 38 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.

Evidence 39 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E.

Evidence 40 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevi

Evidence 41 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 150 µg/mL

Target

Target Organism P.putida

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. a

Evidence 42 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 150 µg/mL

Target

Target Organism P.aeruginosa

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

l), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also

Evidence 43 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 100 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ml), S. dysentariae (MIC 50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 44 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

50 ug/ml), P.putida (MIC150 ug/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 45 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

/ml), P.aeruginosa (MIC150 ug/ml), E. coli (MIC 100 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 46 Activity

Activity

Activity Endpoint 1% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 100 µg/mL

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

1% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Antimicrobial peptides from the skin of a Korean frog, Rana rugosa. | Biochem Biophys Res Commun | 1994

Evidence 47 Activity

Activity

Activity Endpoint IC50

Detail Source Activity Toxicity

Activity Measurement 5.62±1.50 µg/mL

Toxicity Type Cytotoxic

Toxicity Raw

IC50 | 5.62±1.50 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Target Cell Human embryonic kidney HEK293T cells

Source & Reference

Database Source NA

Source Database DBAASP

Reference

In vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines. | Peptides | 2003

Evidence 48 Activity

Activity

Detail Source Activity Toxicity

Toxicity Type Hemolytic

Toxicity Raw

Hemolytic_activity: [Ref.7999137] It has 0.39% hemolytic activity at 0.1 µg/ml, 0.62% hemolytic activity at 1 µg/ml, 0.78% hemolytic activity at 10 µg/ml, 0.86% hemolytic activity at 100 µg/ml against human red blood cells

Target

Target Cell erythrocytes

Source & Reference

Database Source NA

Source Database DRAMP

Reference

Biochem Biophys Res Commun. 1994 Nov 30 205(1):948-954.