Back to search

Peptide record

TPDB04900

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04900
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept i2APP ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFWKKVGSAAWGGVKAAAKGAAVGGLNALAKHIQ
Physicochemical Analysis
C153H243N45O38
RDCEMPTY
A
3320.89
11.12
6
0
18
+5
-0.47
0.253
86.47
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
331.24
3
Residue Composition
number
9
A
0
R
1
N
0
D
0
C
0
E
1
Q
7
G
1
H
1
I
2
L
5
K
0
M
1
F
0
P
1
S
0
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 9 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 7 H: 1 I: 1 L: 2 K: 5 M: 0 F: 1 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 3
Chemical Descriptors
34
C153H243N45O38
3320.89
11.12
+5
-0.47
0.253
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Halocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa. | J Pept Sci | 2009
Evidence 2 Activity

Activity

58% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
58% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.19085906]0% hemolytic activity at 50 µM against sheep erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2009 Jan 15(1):48-55.