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Peptide record

TPDB04853

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB04853
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept AVPpred-BWR
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
TITLSTCAILSKPLGNNGYLCTVTKECMPSSCN
Physicochemical Analysis
C145H244N38O49S5
RDQHFW
T
3464.06
7.84
2
1
10
+1
2.31
0.252
82.73
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1740
50.23
17
Residue Composition
number
1
A
0
R
3
N
0
D
4
C
1
E
0
Q
2
G
0
H
2
I
4
L
2
K
1
M
0
F
2
P
4
S
5
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 0 C: 4 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 2 M: 1 F: 0 P: 2 S: 4 T: 5 W: 0 Y: 1 V: 1
Chemical Descriptors
33
C145H244N38O49S5
3464.06
7.84
+1
2.31
0.252
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

It displayed antimicrobial activity against all L. monocytogenes, MRSA, vancomycin-resistant enterococcus strains tested (Anti-VRE). MIC reached the nM range. In addition, a similar peptide is reported in PLoS One. 2009 Aug 26 4(8):e6788 . Inactivation of the lantibiotic modification enzymes licM1 and licM2 led to loss of antibacterial activity in the isopropanol extract.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

It displayed antimicrobial activity against all L. monocytogenes, MRSA, vancomycin-resistant enterococcus strains tested (Anti-VRE). MIC reached the nM range. In addition, a similar peptide is reported in PLoS One. 2009 Aug 26 4(8):e6788 . Inactivation of the lantibiotic modification enzymes licM1 and licM2 led to loss of antibacterial activity in the isopropanol extract.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

It displayed antimicrobial activity against all L. monocytogenes, MRSA, vancomycin-resistant enterococcus strains tested (Anti-VRE). MIC reached the nM range. In addition, a similar peptide is reported in PLoS One. 2009 Aug 26 4(8):e6788 . Inactivation of the lantibiotic modification enzymes licM1 and licM2 led to loss of antibacterial activity in the isopropanol extract.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

NA

Other

It displayed antimicrobial activity against all L. monocytogenes, MRSA, vancomycin-resistant enterococcus strains tested (Anti-VRE). MIC reached the nM range. In addition, a similar peptide is reported in PLoS One. 2009 Aug 26 4(8):e6788 . Inactivation of the lantibiotic modification enzymes licM1 and licM2 led to loss of antibacterial activity in the isopropanol extract.