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Peptide record

TPDB04846

Antibacterial Antifungal standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB04846
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 31-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GLFDSITQGLKDTAVKLLDKIKCKLSACPPA
Physicochemical Analysis
C146H249N37O43S2
RNEHMWY
LK
3274.93
9.02
5
3
12
+2
5.21
0.158
107.10
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.82
7
Residue Composition
number
3
A
0
R
0
N
3
D
2
C
0
E
1
Q
2
G
0
H
2
I
5
L
5
K
0
M
1
F
2
P
2
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 3 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 5 K: 5 M: 0 F: 1 P: 2 S: 2 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
31
C146H249N37O43S2
3274.93
9.02
+2
5.21
0.158
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus ATCC25923

Source & Reference

NA

Other

st Gram+ bacteria E.faecium 091299 (IS) (MIC >150 uM), E.faecalis 981 (IS) (MIC >150 uM), S.aureus ATCC25923 (MIC >150 uM), S.carnosus KHS (IS) (MIC >150 uM), B.licheniformis X39 (IS) (MIC >150 uM), R. rhodochrou
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

E.coli ATCC25922

Source & Reference

NA

Other

50 uM), B.licheniformis X39 (IS) (MIC >150 uM), R. rhodochrous X15 (IS)(MIC 19 uM), Gram- E.coli ATCC25922 (MIC >150 uM), S.typhi 091408 (IS)(MIC >150 uM), P.aeruginosa (ATCC27853) (MIC >150 uM), P.aeruginosa (
Evidence 3 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC10231

Source & Reference

NA

Other

uM), P.aeruginosa (ATCC27853) (MIC >150 uM), P. faecalis X29 (IS) (MIC 9.5 uM), and fungi C.albicans ATCC10231 (MIC>150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus ATCC25923

Source & Reference

Antifungipept

Other

st Gram+ bacteria E.faecium 091299 (IS) (MIC >150 uM), E.faecalis 981 (IS) (MIC >150 uM), S.aureus ATCC25923 (MIC >150 uM), S.carnosus KHS (IS) (MIC >150 uM), B.licheniformis X39 (IS) (MIC >150 uM), R. rhodochrou
Evidence 5 Activity

Activity

MIC
Antifungal
>150 µM

Target

E.coli ATCC25922

Source & Reference

Antifungipept

Other

50 uM), B.licheniformis X39 (IS) (MIC >150 uM), R. rhodochrous X15 (IS)(MIC 19 uM), Gram- E.coli ATCC25922 (MIC >150 uM), S.typhi 091408 (IS)(MIC >150 uM), P.aeruginosa (ATCC27853) (MIC >150 uM), P.aeruginosa (
Evidence 6 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC10231

Source & Reference

Antifungipept

Other

uM), P.aeruginosa (ATCC27853) (MIC >150 uM), P. faecalis X29 (IS) (MIC 9.5 uM), and fungi C.albicans ATCC10231 (MIC>150 uM).