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Peptide record

TPDB04825

Antibacterial Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB04825
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
YTLGIKILWSAYKHRKTIEKSFNKGFYH
Physicochemical Analysis
C164H246N42O39
DCQMPV
K
3430.02
10.38
8
1
12
+5
1.53
-0.625
73.21
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
9970
290.67
8
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
1
E
0
Q
2
G
2
H
3
I
2
L
5
K
0
M
2
F
0
P
2
S
2
T
1
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 2 I: 3 L: 2 K: 5 M: 0 F: 2 P: 0 S: 2 T: 2 W: 1 Y: 3 V: 0
Chemical Descriptors
28
C164H246N42O39
3430.02
10.38
+5
1.53
-0.625
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020