TPDB04808

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism L. monocytogenes

Source & Reference

Database Source NA

Other

Evidence Text

Active against Gram-positive S. aureus (MRSA), E. faecalis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM),

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism M. luteus

Source & Reference

Database Source NA

Other

Evidence Text

S. aureus (MRSA), E. faecalis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source NA

Other

Evidence Text

alis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism S. saprophiticus

Source & Reference

Database Source NA

Other

Evidence Text

L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 u

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus agalactiae

Source & Reference

Database Source NA

Other

Evidence Text

, M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus bovis

Source & Reference

Database Source NA

Other

Evidence Text

idermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 u

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism S. equisimilis

Source & Reference

Database Source NA

Other

Evidence Text

saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 u

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. mitis

Source & Reference

Database Source NA

Other

Evidence Text

agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 u

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. pneumoniae

Source & Reference

Database Source NA

Other

Evidence Text

), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus pyogenes

Source & Reference

Database Source NA

Other

Evidence Text

equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 u

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. iniae

Source & Reference

Database Source NA

Other

Evidence Text

mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 u

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism V. cholera

Source & Reference

Database Source NA

Other

Evidence Text

IC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneum

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source NA

Other

Evidence Text

s (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 110-20 µM

Target

Target Organism Enterobacter cloacae

Source & Reference

Database Source NA

Other

Evidence Text

iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M.

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism Enterobacter aerogenes

Source & Reference

Database Source NA

Other

Evidence Text

am-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source NA

Other

Evidence Text

.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S.

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source NA

Other

Evidence Text

), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 u

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism M. catarrhalis

Source & Reference

Database Source NA

Other

Evidence Text

uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 u

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source NA

Other

Evidence Text

), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM),

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism S. choleraesuis

Source & Reference

Database Source NA

Other

Evidence Text

M), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. s

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism S. typhimurium

Source & Reference

Database Source NA

Other

Evidence Text

catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enteroc

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism S. flexneri

Source & Reference

Database Source NA

Other

Evidence Text

, S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism S. sonnei

Source & Reference

Database Source NA

Other

Evidence Text

uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fum

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism Y. enterocolitica

Source & Reference

Database Source NA

Other

Evidence Text

10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxyspor

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.56-3.12 µM

Target

Target Organism N. crassa

Source & Reference

Database Source NA

Other

Evidence Text

C 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.7

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50-100 µM

Target

Target Organism A. fumigatus

Source & Reference

Database Source NA

Other

Evidence Text

10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.78-1.56 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source NA

Other

Evidence Text

2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lus

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.39-0.78 µM

Target

Target Organism F. culmorum

Source & Reference

Database Source NA

Other

Evidence Text

crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tr

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism C. glabrata

Source & Reference

Database Source NA

Other

Evidence Text

), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism C. lusitania

Source & Reference

Database Source NA

Other

Evidence Text

56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism C. tropicalis

Source & Reference

Database Source NA

Other

Evidence Text

8 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism L. monocytogenes

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

Active against Gram-positive S. aureus (MRSA), E. faecalis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM),

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism M. luteus

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

S. aureus (MRSA), E. faecalis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

alis (anti-VRE) (MIC 5-10 uM), L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism S. saprophiticus

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

L. monocytogenes (MIC 2.5-5 uM), M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 u

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus agalactiae

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

, M. luteus (MIC 10-20 uM), S. epidermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus bovis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

idermidis (MIC 5-10 uM), S. saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 u

Evidence 38 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism S. equisimilis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

saprophiticus (MIC 5-10 uM), S. agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 u

Evidence 39 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. mitis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

agalactiae (MIC 1.25-2.5 uM), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 u

Evidence 40 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. pneumoniae

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

), S. bovis (MIC 1.25-2.5 uM), S. equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC

Evidence 41 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism Streptococcus pyogenes

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

equisimilis (MIC 2.5-5 uM), S. mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 u

Evidence 42 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.25-2.5 µM

Target

Target Organism S. iniae

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

mitis (MIC 1.25-2.5 uM), S. pneumoniae (MIC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 u

Evidence 43 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism V. cholera

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

IC 1.25-2.5 uM), S. pyogenes (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneum

Evidence 44 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

s (MIC 1.25-2.5 uM), S. iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K

Evidence 45 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 110-20 µM

Target

Target Organism Enterobacter cloacae

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

iniae (MIC 1.25-2.5 uM), Gram-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M.

Evidence 46 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism Enterobacter aerogenes

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

am-negative V. cholera (MIC 2.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P

Evidence 47 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

.5-5 uM), E. coli (MIC 5-10 uM), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S.

Evidence 48 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

), E. cloacae (MIC 110-20 uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 u

Evidence 49 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism M. catarrhalis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

uM), E. aerogenes (MIC 10-20 uM), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 u

Evidence 50 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

), K. pneumoniae (MIC 2.5-5 uM), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM),

Evidence 51 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism S. choleraesuis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

M), K. oxytoca (MIC 5-10 uM), M. catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. s

Evidence 52 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism S. typhimurium

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

catarrhalis (MIC 2.5-5 uM), P. aeruginosa (MIC 5-10 uM), S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enteroc

Evidence 53 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism S. flexneri

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

, S. choleraesuis (MIC 10-20 uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (

Evidence 54 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism S. sonnei

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

uM), S. typhimurium (MIC 10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fum

Evidence 55 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism Y. enterocolitica

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

10-20 uM), S-arizonae (MIC >20 uM), S. flexneri (MIC 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxyspor

Evidence 56 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.56-3.12 µM

Target

Target Organism N. crassa

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

C 2.5-5 uM), S. sonnei (MIC 5-10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.7

Evidence 57 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50-100 µM

Target

Target Organism A. fumigatus

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

10 uM), Y. enterocolitica (MIC 2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C

Evidence 58 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.78-1.56 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

2.5-5 uM), filamentous fungi N. crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lus

Evidence 59 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.39-0.78 µM

Target

Target Organism F. culmorum

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

crassa (MIC 1.56-3.12 uM), A. fumigatus (MIC 50-100 uM), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tr

Evidence 60 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism C. glabrata

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

), F. oxysporum (MIC 0.78-1.56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024

Evidence 61 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism C. lusitania

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

56 uM), F. culmorum (MIC 0.39-0.78 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024

Evidence 62 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism C. tropicalis

Source & Reference

Database Source CAFPdb Antifungipept

Other

Evidence Text

8 uM), yeast (MIC 10-20 uM), C. glabrata (MIC 10-20 uM), C. lusitania (MIC 10-20 uM), and C. tropicalis (MIC 10-20 uM). Updated 12/2024