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Peptide record

TPDB04742

Antibacterial Antifungal standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB04742
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VKGSWSKKFEVIA
Physicochemical Analysis
C70H111N17O18
RNDCQHLMPTY
K
1478.75
10.32
3
1
6
+2
1.94
-0.046
82.31
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
371.93
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
1
I
0
L
3
K
0
M
1
F
0
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 3 M: 0 F: 1 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
13
C70H111N17O18
1478.75
10.32
+2
1.94
-0.046
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

B. subtilis JH642

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Mainly active against G- bacteria (see beloe) and only weakly active against Gram+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

bacteria (see beloe) and only weakly active against Gram+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), an
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

C. jejuni NCTC 11168

Source & Reference

dbAMP DRAMP

Other

m+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also acti
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli DH5alpha

Source & Reference

dbAMP DRAMP

Other

. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also active against resistant strains o
Evidence 5 Activity

Activity

MIC
Antibacterial
25 µM

Target

S. enterica serovar Typhimurium

Source & Reference

dbAMP DRAMP

Other

Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also active against resistant strains of K. pneumoniae, A. baumannii, and E. coli. It is
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

i. It is not active

Source & Reference

dbAMP DRAMP

Other

C 25 uM). Also active against resistant strains of K. pneumoniae, A. baumannii, and E. coli. It is not active (MIC>100 uM) against C.maltaromaticum UAL26, E.faecium ATCC 19434, L.lactis subsp. cremoris HP, L.mono
Evidence 7 Activity

Activity

MIC
Antifungal
50 µM

Target

B. subtilis JH642

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Mainly active against G- bacteria (see beloe) and only weakly active against Gram+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM
Evidence 8 Activity

Activity

MIC
Antifungal
100 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP Antifungipept

Other

bacteria (see beloe) and only weakly active against Gram+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), an
Evidence 9 Activity

Activity

MIC
Antifungal
100 µM

Target

C. jejuni NCTC 11168

Source & Reference

dbAMP DRAMP Antifungipept

Other

m+ B. subtilis JH642 (MIC 50 uM), S. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also acti
Evidence 10 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli DH5alpha

Source & Reference

dbAMP DRAMP Antifungipept

Other

. aureus ATCC 25923 (MIC 100 uM), Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also active against resistant strains o
Evidence 11 Activity

Activity

MIC
Antifungal
25 µM

Target

S. enterica serovar Typhimurium

Source & Reference

dbAMP DRAMP Antifungipept

Other

Gram- food pathogens C. jejuni NCTC 11168 (MIC 100 uM), E. coli DH5alpha (MIC 50 uM), and S. enterica serovar Typhimurium (MIC 25 uM). Also active against resistant strains of K. pneumoniae, A. baumannii, and E. coli. It is
Evidence 12 Activity

Activity

MIC
Antifungal
>100 µM

Target

i. It is not active

Source & Reference

dbAMP DRAMP Antifungipept

Other

C 25 uM). Also active against resistant strains of K. pneumoniae, A. baumannii, and E. coli. It is not active (MIC>100 uM) against C.maltaromaticum UAL26, E.faecium ATCC 19434, L.lactis subsp. cremoris HP, L.mono