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Peptide record

TPDB04711

Antibacterial Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB04711
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWRWWKFV
Physicochemical Analysis
C65H86N18O9
ANDCEQGHILMPSTY
W
1263.51
12.41
3
0
5
+3
-4.00
-1.075
36.25
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
1305.88
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
8
C65H86N18O9
1263.51
12.41
+3
-4.00
-1.075
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<5% Hemolysis | 200 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
In Vitro and Ex Vivo Efficacy of Novel Trp-Arg Rich Analogue of alpha-MSH Against Staphylococcus aureus. | ACS Omega | 2020
Evidence 2 Activity

Activity

<=22±4% Cytotoxicity
Toxicity
60 µM
Cytotoxic
<=22±4% Cytotoxicity | 60 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
In Vitro and Ex Vivo Efficacy of Novel Trp-Arg Rich Analogue of alpha-MSH Against Staphylococcus aureus. | ACS Omega | 2020