Peptide record

TPDB04678

Antibacterial Anticancer Antifungal Antiparasitic standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB04678
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
MGAIAKLVAKFGWPIVKKYYKQIMQFIGEGWAINKIIEWIKKHI
Physicochemical Analysis
C252H392N60O54S2
RDCST
I
5190.37
10.44
9
2
25
+6
0.95
0.202
110.91
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
19480
375.31
5
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
2
E
2
Q
4
G
1
H
9
I
1
L
8
K
2
M
2
F
1
P
0
S
0
T
3
W
2
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 2 Q: 2 G: 4 H: 1 I: 9 L: 1 K: 8 M: 2 F: 2 P: 1 S: 0 T: 0 W: 3 Y: 2 V: 2
Chemical Descriptors
44
C252H392N60O54S2
5190.37
10.44
+6
0.95
0.202
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
EntL50A and EntL50B both possess antimicrobial activity on their own, with EntL50A being the most active. Supernatant containing Enterocin A5-11 inhibited several Lactobacillus spp. and food-borne pathogens E. coli, S. aureus and L. innocua.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
EntL50A and EntL50B both possess antimicrobial activity on their own, with EntL50A being the most active. Supernatant containing Enterocin A5-11 inhibited several Lactobacillus spp. and food-borne pathogens E. coli, S. aureus and L. innocua.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

EntL50A and EntL50B both possess antimicrobial activity on their own, with EntL50A being the most active. Supernatant containing Enterocin A5-11 inhibited several Lactobacillus spp. and food-borne pathogens E. coli, S. aureus and L. innocua.