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Peptide record

TPDB04669

Antibacterial Anticancer Antifungal Antiparasitic standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB04669
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AISYGNGVYCNKEKCWVNKAENKQAITGIVIGGWASSLAGMGH
Physicochemical Analysis
C199H310N56O59S3
RDFP
G
4527.17
8.94
5
2
18
+2
3.09
-0.077
77.21
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
14105
311.56
13
Residue Composition
number
5
A
0
R
4
N
0
D
2
C
2
E
1
Q
7
G
1
H
4
I
1
L
4
K
1
M
0
F
0
P
3
S
1
T
2
W
2
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 4 D: 0 C: 2 E: 2 Q: 1 G: 7 H: 1 I: 4 L: 1 K: 4 M: 1 F: 0 P: 0 S: 3 T: 1 W: 2 Y: 2 V: 3
Chemical Descriptors
43
C199H310N56O59S3
4527.17
8.94
+2
3.09
-0.077
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
spot-on-lawn test at 50 ug/ml: Active against C. divergens LV13, C. piscicola UAL26, L. plantarum ATCC 4008, P. parvulus ATCC 19371, L. monocytogenes ATCC 15313, L. innocua ATCC 33090, E. faecium ATCC 11576 or 19434, and E. faecalis ATCC 19433. Variant: Carnobacteriocin B1 has the same amino acid sequence as carnobacteriocin BM1 with residue Met41 oxidized (sulfoxide). This oxidation reduces the activity of the peptide by a factor of 4-8. Updated 7/2021 2/2023
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
spot-on-lawn test at 50 ug/ml: Active against C. divergens LV13, C. piscicola UAL26, L. plantarum ATCC 4008, P. parvulus ATCC 19371, L. monocytogenes ATCC 15313, L. innocua ATCC 33090, E. faecium ATCC 11576 or 19434, and E. faecalis ATCC 19433. Variant: Carnobacteriocin B1 has the same amino acid sequence as carnobacteriocin BM1 with residue Met41 oxidized (sulfoxide). This oxidation reduces the activity of the peptide by a factor of 4-8. Updated 7/2021 2/2023
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

spot-on-lawn test at 50 ug/ml: Active against C. divergens LV13, C. piscicola UAL26, L. plantarum ATCC 4008, P. parvulus ATCC 19371, L. monocytogenes ATCC 15313, L. innocua ATCC 33090, E. faecium ATCC 11576 or 19434, and E. faecalis ATCC 19433. Variant: Carnobacteriocin B1 has the same amino acid sequence as carnobacteriocin BM1 with residue Met41 oxidized (sulfoxide). This oxidation reduces the activity of the peptide by a factor of 4-8. Updated 7/2021 2/2023