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Peptide record

TPDB04647

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB04647
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KPAWCWYTLAMCGAGYDSGTCDYMYSHCFGIKHHSSGSSSYHC
Physicochemical Analysis
C210H289N55O62S7
RNEQV
S
4800.36
7.11
6
2
15
+0
-2.60
-0.319
25.12
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
18700
389.55
19
Residue Composition
number
3
A
0
R
0
N
2
D
5
C
0
E
0
Q
5
G
4
H
1
I
1
L
2
K
2
M
1
F
1
P
7
S
2
T
2
W
5
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 2 C: 5 E: 0 Q: 0 G: 5 H: 4 I: 1 L: 1 K: 2 M: 2 F: 1 P: 1 S: 7 T: 2 W: 2 Y: 5 V: 0
Chemical Descriptors
43
C210H289N55O62S7
4800.36
7.11
+0
-2.60
-0.319
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
incubation with 200 nM GccF for 5 h resulted in only 5% cell death of L. plantarum (ATCC 8014 cultures). Rather, purified GccF caused rapid and sustained bacteriostasis (IC50 ~2 nM).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
incubation with 200 nM GccF for 5 h resulted in only 5% cell death of L. plantarum (ATCC 8014 cultures). Rather, purified GccF caused rapid and sustained bacteriostasis (IC50 ~2 nM).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

incubation with 200 nM GccF for 5 h resulted in only 5% cell death of L. plantarum (ATCC 8014 cultures). Rather, purified GccF caused rapid and sustained bacteriostasis (IC50 ~2 nM).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

incubation with 200 nM GccF for 5 h resulted in only 5% cell death of L. plantarum (ATCC 8014 cultures). Rather, purified GccF caused rapid and sustained bacteriostasis (IC50 ~2 nM).