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Peptide record

TPDB04641

Antibacterial Antifungal standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB04641
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 43-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
NIGLFTSTCFSSQCFSSKCFTDTCFSSNCFTGRHQCGYTHGSC
Physicochemical Analysis
C198H287N55O65S7
AEMPWV
S
4702.21
7.57
4
1
9
+1
-1.40
-0.074
18.14
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1865
39.66
26
Residue Composition
number
0
A
1
R
2
N
1
D
7
C
0
E
2
Q
4
G
2
H
1
I
1
L
1
K
0
M
6
F
0
P
8
S
6
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 1 C: 7 E: 0 Q: 2 G: 4 H: 2 I: 1 L: 1 K: 1 M: 0 F: 6 P: 0 S: 8 T: 6 W: 0 Y: 1 V: 0
Chemical Descriptors
43
C198H287N55O65S7
4702.21
7.57
+1
-1.40
-0.074
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.58 µM

Target

Escherichia coli

Source & Reference

NA

Other

ureus (MIC ~3 uM), L. monocytogenes (MIC ~1 uM), B. subtilis (~1.5 uM) and Gram- bacteria E. coli (MIC 1.58 uM), P. aeruginosa (MIC 0.75 uM) and V. cholerae (MIC ~7 uM). 30 min incubation with 5 x MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
0.75 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

onocytogenes (MIC ~1 uM), B. subtilis (~1.5 uM) and Gram- bacteria E. coli (MIC 1.58 uM), P. aeruginosa (MIC 0.75 uM) and V. cholerae (MIC ~7 uM). 30 min incubation with 5 x MIC killed 100% MRSA.
Evidence 3 Activity

Activity

MIC
Antifungal
1.58 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

ureus (MIC ~3 uM), L. monocytogenes (MIC ~1 uM), B. subtilis (~1.5 uM) and Gram- bacteria E. coli (MIC 1.58 uM), P. aeruginosa (MIC 0.75 uM) and V. cholerae (MIC ~7 uM). 30 min incubation with 5 x MIC
Evidence 4 Activity

Activity

MIC
Antifungal
0.75 µM

Target

Pseudomonas aeruginosa

Source & Reference

Antifungipept

Other

onocytogenes (MIC ~1 uM), B. subtilis (~1.5 uM) and Gram- bacteria E. coli (MIC 1.58 uM), P. aeruginosa (MIC 0.75 uM) and V. cholerae (MIC ~7 uM). 30 min incubation with 5 x MIC killed 100% MRSA.