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Peptide record

TPDB04616

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04616
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCR
Physicochemical Analysis
C165H262N60O56S8
DEHIKMFPV
C
4238.74
8.31
4
0
8
+4
0.72
-0.513
27.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8980
211.86
23
Residue Composition
number
3
A
4
R
1
N
0
D
8
C
0
E
6
Q
7
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
5
S
1
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 3 R: 4 N: 1 D: 0 C: 8 E: 0 Q: 6 G: 7 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 5 T: 1 W: 1 Y: 2 V: 0
Chemical Descriptors
40
C165H262N60O56S8
4238.74
8.31
+4
0.72
-0.513
Evidence Records 24 records
Evidence 1 Activity

Activity

IC50
Antibacterial
2 µg/mL

Target

B. cinerea

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug
Evidence 2 Activity

Activity

IC50
Antibacterial
4 µg/mL

Target

C. langenarium

Source & Reference

dbAMP DRAMP

Other

fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/
Evidence 3 Activity

Activity

IC50
Antibacterial
3 µg/mL

Target

S. sclerotiorum

Source & Reference

dbAMP DRAMP

Other

n the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml),
Evidence 4 Activity

Activity

IC50
Antibacterial
2.5 µg/mL

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Py
Evidence 5 Activity

Activity

IC50
Antibacterial
75 µg/mL

Target

R. solani

Source & Reference

dbAMP DRAMP

Other

sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug
Evidence 6 Activity

Activity

IC50
Antibacterial
0.6 µg/mL

Target

P. capsici

Source & Reference

dbAMP DRAMP

Other

, F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. su
Evidence 7 Activity

Activity

IC50
Antibacterial
2 µg/mL

Target

P. parasitica

Source & Reference

dbAMP DRAMP

Other

. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.
Evidence 8 Activity

Activity

IC50
Antibacterial
20 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

g/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.
Evidence 9 Activity

Activity

IC50
Antifungal
2 µg/mL

Target

B. cinerea

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug
Evidence 10 Activity

Activity

IC50
Antifungal
4 µg/mL

Target

C. langenarium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/
Evidence 11 Activity

Activity

IC50
Antifungal
3 µg/mL

Target

S. sclerotiorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

n the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml),
Evidence 12 Activity

Activity

IC50
Antifungal
2.5 µg/mL

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Py
Evidence 13 Activity

Activity

IC50
Antifungal
75 µg/mL

Target

R. solani

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug
Evidence 14 Activity

Activity

IC50
Antifungal
0.6 µg/mL

Target

P. capsici

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. su
Evidence 15 Activity

Activity

IC50
Antifungal
2 µg/mL

Target

P. parasitica

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.
Evidence 16 Activity

Activity

IC50
Antifungal
20 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.
Evidence 17 Activity

Activity

IC50
Antiparasitic
2 µg/mL

Target

B. cinerea

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug
Evidence 18 Activity

Activity

IC50
Antiparasitic
4 µg/mL

Target

C. langenarium

Source & Reference

DRAMP

Other

fungi with or without chitin in the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/
Evidence 19 Activity

Activity

IC50
Antiparasitic
3 µg/mL

Target

S. sclerotiorum

Source & Reference

DRAMP

Other

n the membranes. Active against B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml),
Evidence 20 Activity

Activity

IC50
Antiparasitic
2.5 µg/mL

Target

F. oxysporum

Source & Reference

DRAMP

Other

B. cinerea (IC50 2 ug/ml), C. langenarium (IC50 4 ug/ml), S. sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Py
Evidence 21 Activity

Activity

IC50
Antiparasitic
75 µg/mL

Target

R. solani

Source & Reference

DRAMP

Other

sclerotiorum (IC50 3 ug/ml), F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug
Evidence 22 Activity

Activity

IC50
Antiparasitic
0.6 µg/mL

Target

P. capsici

Source & Reference

DRAMP

Other

, F. oxysporum (IC50 2.5 ug/ml), S. cereÍisiae (IC50 8 ug/ml), R. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. su
Evidence 23 Activity

Activity

IC50
Antiparasitic
2 µg/mL

Target

P. parasitica

Source & Reference

DRAMP

Other

. solani (IC50 75 ug/ml), P. capsici (IC50 0.6 ug/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.
Evidence 24 Activity

Activity

IC50
Antiparasitic
20 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

g/ml), Pythium spp. (IC50 2.5 ug/ml), and P. parasitica (IC50 2 ug/ml). It also inhibited B. subtilis (IC50 20 ug/ml) but not E.coli, A.tumefaciens.