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Peptide record

TPDB04586

Antibacterial Antifungal standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB04586
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 38-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INTWNTTATSTSIIISETFGNKGKVCTYTVECVNNCRG
Physicochemical Analysis
C175H281N49O60S3
DQHLMP
T
4127.63
8.01
3
2
11
+1
4.63
-0.145
66.58
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
7115
172.38
20
Residue Composition
number
1
A
1
R
5
N
0
D
3
C
2
E
0
Q
3
G
0
H
4
I
0
L
2
K
0
M
1
F
0
P
3
S
8
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 5 D: 0 C: 3 E: 2 Q: 0 G: 3 H: 0 I: 4 L: 0 K: 2 M: 0 F: 1 P: 0 S: 3 T: 8 W: 1 Y: 1 V: 3
Chemical Descriptors
38
C175H281N49O60S3
4127.63
8.01
+1
4.63
-0.145
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µM

Target

L. monocytogenes LM201

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
9619, B. cereus ATCC 14579, B. thuringiensis BMB171, B. pumilus SCG I , B. subtilis Bsn5, L. monocytogenes LM201 (MIC 6.25 uM), L. monocytogenes LM605, S. aureus ATCC 43300, S. sciuri Bom1, B. amyloliquefaciens X1 (M
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

B. amyloliquefaciens X1

Source & Reference

dbAMP DRAMP

Other

ogenes LM201 (MIC 6.25 uM), L. monocytogenes LM605, S. aureus ATCC 43300, S. sciuri Bom1, B. amyloliquefaciens X1 (MIC 12.5 uM), S. aureus CMCC 26003, MRSA (MIC 25 uM), and E. faecalis ATCC 29212 (MIC 50 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP

Other

Bom1, B. amyloliquefaciens X1 (MIC 12.5 uM), S. aureus CMCC 26003, MRSA (MIC 25 uM), and E. faecalis ATCC 29212 (MIC 50 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
6.25 µM

Target

L. monocytogenes LM201

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
9619, B. cereus ATCC 14579, B. thuringiensis BMB171, B. pumilus SCG I , B. subtilis Bsn5, L. monocytogenes LM201 (MIC 6.25 uM), L. monocytogenes LM605, S. aureus ATCC 43300, S. sciuri Bom1, B. amyloliquefaciens X1 (M
Evidence 5 Activity

Activity

MIC
Antifungal
12.5 µM

Target

B. amyloliquefaciens X1

Source & Reference

dbAMP DRAMP Antifungipept

Other

ogenes LM201 (MIC 6.25 uM), L. monocytogenes LM605, S. aureus ATCC 43300, S. sciuri Bom1, B. amyloliquefaciens X1 (MIC 12.5 uM), S. aureus CMCC 26003, MRSA (MIC 25 uM), and E. faecalis ATCC 29212 (MIC 50 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
50 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP Antifungipept

Other

Bom1, B. amyloliquefaciens X1 (MIC 12.5 uM), S. aureus CMCC 26003, MRSA (MIC 25 uM), and E. faecalis ATCC 29212 (MIC 50 uM).