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Peptide record

TPDB04573

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB04573
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KYYGNGVTCGKHSCSVNWGQAFSCSVSHLANFGHGKC
Physicochemical Analysis
C170H249N51O50S4
RDEIMP
G
3935.40
8.69
6
0
11
+3
0.90
-0.278
39.46
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8730
221.83
16
Residue Composition
number
2
A
0
R
3
N
0
D
4
C
0
E
1
Q
6
G
3
H
0
I
1
L
3
K
0
M
2
F
0
P
5
S
1
T
1
W
2
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 0 C: 4 E: 0 Q: 1 G: 6 H: 3 I: 0 L: 1 K: 3 M: 0 F: 2 P: 0 S: 5 T: 1 W: 1 Y: 2 V: 3
Chemical Descriptors
37
C170H249N51O50S4
3935.40
8.69
+3
0.90
-0.278
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
An aliquot of 10 ul cell-free culture supernatant fluid (not the pure peptide) was spotted onto an agar plate (0·7% w/v agar) seeded with active growing cells of the test organism (approximately 106 cells ml). Active against B. cereus, C. sporogenes, E. faecalis, L. brevis, L. buchnerii, L. curvatus, L. fermentum LMG 13554, L. fermentum ATCC 9338, L. helveticus LMG 13555, L. plantarum ATCC 14917, L. plantarum LMG 13556, L. reuteri DSM 20016, L. innocua LMG 13568, L. monocytogenes LM1, O. oeni ML 34 or 19Ci, L. oenos, V. oenos, P. acidilactici, P. pentosaceus LMG 13560, P. acidipropionici LMG 13572, Propionibacterium sp. LMG 13573, S. carnosum LMG 13567, and S. thermophilus LMG 13565. Partially puirified peptide is weakly active against O. oeni (previously L. oenos).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
An aliquot of 10 ul cell-free culture supernatant fluid (not the pure peptide) was spotted onto an agar plate (0·7% w/v agar) seeded with active growing cells of the test organism (approximately 106 cells ml). Active against B. cereus, C. sporogenes, E. faecalis, L. brevis, L. buchnerii, L. curvatus, L. fermentum LMG 13554, L. fermentum ATCC 9338, L. helveticus LMG 13555, L. plantarum ATCC 14917, L. plantarum LMG 13556, L. reuteri DSM 20016, L. innocua LMG 13568, L. monocytogenes LM1, O. oeni ML 34 or 19Ci, L. oenos, V. oenos, P. acidilactici, P. pentosaceus LMG 13560, P. acidipropionici LMG 13572, Propionibacterium sp. LMG 13573, S. carnosum LMG 13567, and S. thermophilus LMG 13565. Partially puirified peptide is weakly active against O. oeni (previously L. oenos).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

An aliquot of 10 ul cell-free culture supernatant fluid (not the pure peptide) was spotted onto an agar plate (0·7% w/v agar) seeded with active growing cells of the test organism (approximately 106 cells ml). Active against B. cereus, C. sporogenes, E. faecalis, L. brevis, L. buchnerii, L. curvatus, L. fermentum LMG 13554, L. fermentum ATCC 9338, L. helveticus LMG 13555, L. plantarum ATCC 14917, L. plantarum LMG 13556, L. reuteri DSM 20016, L. innocua LMG 13568, L. monocytogenes LM1, O. oeni ML 34 or 19Ci, L. oenos, V. oenos, P. acidilactici, P. pentosaceus LMG 13560, P. acidipropionici LMG 13572, Propionibacterium sp. LMG 13573, S. carnosum LMG 13567, and S. thermophilus LMG 13565. Partially puirified peptide is weakly active against O. oeni (previously L. oenos).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

An aliquot of 10 ul cell-free culture supernatant fluid (not the pure peptide) was spotted onto an agar plate (0·7% w/v agar) seeded with active growing cells of the test organism (approximately 106 cells ml). Active against B. cereus, C. sporogenes, E. faecalis, L. brevis, L. buchnerii, L. curvatus, L. fermentum LMG 13554, L. fermentum ATCC 9338, L. helveticus LMG 13555, L. plantarum ATCC 14917, L. plantarum LMG 13556, L. reuteri DSM 20016, L. innocua LMG 13568, L. monocytogenes LM1, O. oeni ML 34 or 19Ci, L. oenos, V. oenos, P. acidilactici, P. pentosaceus LMG 13560, P. acidipropionici LMG 13572, Propionibacterium sp. LMG 13573, S. carnosum LMG 13567, and S. thermophilus LMG 13565. Partially puirified peptide is weakly active against O. oeni (previously L. oenos).