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Peptide record

TPDB04563

Antibacterial Anticancer Antifungal Antiparasitic standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB04563
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
TSYGNGVHCNKSKCWIDVSELETYKAGTVSNPKDILW
Physicochemical Analysis
C183H280N48O58S2
RQMF
KS
4144.64
7.00
5
4
12
+0
6.34
-0.535
68.38
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
14105
340.32
14
Residue Composition
number
1
A
0
R
3
N
2
D
2
C
2
E
0
Q
3
G
1
H
2
I
2
L
4
K
0
M
0
F
1
P
4
S
3
T
2
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 2 C: 2 E: 2 Q: 0 G: 3 H: 1 I: 2 L: 2 K: 4 M: 0 F: 0 P: 1 S: 4 T: 3 W: 2 Y: 2 V: 3
Chemical Descriptors
37
C183H280N48O58S2
4144.64
7.00
+0
6.34
-0.535
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Lactococcin MMFII contains the N-terminal YGNGV consensus motif and is active against Listeria: L. ivanovii BUG 469 (generated 2mm zone of groth inhibition at 2.5 uM) and L. lactis cremoris 1160 (generated 2mm zone of groth inhibition at 1.42 nM). Thus, it belongs to the class IIa bacteriocins figuring the first example of such a bacteriocin produced by a lactococcal strain. See AP00923 for more info. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Lactococcin MMFII contains the N-terminal YGNGV consensus motif and is active against Listeria: L. ivanovii BUG 469 (generated 2mm zone of groth inhibition at 2.5 uM) and L. lactis cremoris 1160 (generated 2mm zone of groth inhibition at 1.42 nM). Thus, it belongs to the class IIa bacteriocins figuring the first example of such a bacteriocin produced by a lactococcal strain. See AP00923 for more info. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Lactococcin MMFII contains the N-terminal YGNGV consensus motif and is active against Listeria: L. ivanovii BUG 469 (generated 2mm zone of groth inhibition at 2.5 uM) and L. lactis cremoris 1160 (generated 2mm zone of groth inhibition at 1.42 nM). Thus, it belongs to the class IIa bacteriocins figuring the first example of such a bacteriocin produced by a lactococcal strain. See AP00923 for more info. Updated 7/2021