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Peptide record

TPDB04548

Antibacterial Antifungal standard
35 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04548
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
SILSTLKDVGISAIKNAGSGVLKTLLCKLNKNCEK
Physicochemical Analysis
C159H284N44O49S2
RQHMFPWY
LK
3660.39
9.98
6
2
13
+4
6.31
0.189
122.57
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.41
11
Residue Composition
number
2
A
0
R
3
N
1
D
2
C
1
E
0
Q
3
G
0
H
3
I
6
L
6
K
0
M
0
F
0
P
4
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 1 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 6 K: 6 M: 0 F: 0 P: 0 S: 4 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
35
C159H284N44O49S2
3660.39
9.98
+4
6.31
0.189
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

E. faecium 091299

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

Enterococcus faecalis 981

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 4 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

N. asteroides 201118

Source & Reference

NA

Other

eus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

NA

Other

100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli ATCC 25922

Source & Reference

NA

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC
Evidence 7 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

P. faecalis X29

Source & Reference

NA

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
>100 µM

Target

C.glabrata 090902

Source & Reference

NA

Other

7 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
100 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6
Evidence 10 Activity

Activity

MIC
Antifungal
50 µM

Target

E. faecium 091299

Source & Reference

Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 11 Activity

Activity

MIC
Antifungal
100 µM

Target

Enterococcus faecalis 981

Source & Reference

Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 12 Activity

Activity

MIC
Antifungal
6.3 µM

Target

N. asteroides 201118

Source & Reference

Antifungipept

Other

eus ATCC 25923 (MIC 100 uM), E. faecium 091299 (MIC 50 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

Antifungipept

Other

100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli ATCC 25922

Source & Reference

Antifungipept

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC
Evidence 15 Activity

Activity

MIC
Antifungal
6.3 µM

Target

P. faecalis X29

Source & Reference

Antifungipept

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 16 Activity

Activity

MIC
Antifungal
>100 µM

Target

C.glabrata 090902

Source & Reference

Antifungipept

Other

7 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 6.3 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).