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Peptide record

TPDB04511

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB04511
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WKSESVCTPGCVTGLLQTCFLQTITCNCKISK
Physicochemical Analysis
C150H247N39O46S5
ARDHMY
CT
3493.14
8.14
3
1
9
+2
1.79
0.287
79.06
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5750
164.61
16
Residue Composition
number
0
A
0
R
1
N
0
D
5
C
1
E
2
Q
2
G
0
H
2
I
3
L
3
K
0
M
1
F
1
P
3
S
5
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 5 E: 1 Q: 2 G: 2 H: 0 I: 2 L: 3 K: 3 M: 0 F: 1 P: 1 S: 3 T: 5 W: 1 Y: 0 V: 2
Chemical Descriptors
32
C150H247N39O46S5
3493.14
8.14
+2
1.79
0.287
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
unsuccinylated Entianin was active against several Gram-positive pathogens, such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. fae
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP

Other

such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-
Evidence 3 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP

Other

s ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-8 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
unsuccinylated Entianin was active against several Gram-positive pathogens, such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. fae
Evidence 5 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP Antifungipept

Other

such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-
Evidence 6 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP Antifungipept

Other

s ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-8 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
unsuccinylated Entianin was active against several Gram-positive pathogens, such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. fae
Evidence 8 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

DRAMP

Other

such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-
Evidence 9 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

DRAMP

Other

s ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-8 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
unsuccinylated Entianin was active against several Gram-positive pathogens, such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. fae
Evidence 11 Activity

Activity

MIC
Antiviral
16 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

DRAMP

Other

such as S. aureus ATCC 29213 (MIC 4-8 ug/ml), S. aureus ATCC 43300 (MRSA) (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-
Evidence 12 Activity

Activity

MIC
Antiviral
4-8 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

DRAMP

Other

s ATCC 29212 (MIC 16 ug/ml), E. faecalis ATCC 51299 (VRE) (MIC 6-16 ug/ml, anti-VRE), and M. luteus ATCC 9341 (MIC 4-8 ug/ml).