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Peptide record

TPDB04504

Antibacterial Anticancer Antifungal Antiparasitic standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB04504
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SASIVKTTIKASKKLCRGFTLTCGCHFTGKK
Physicochemical Analysis
C145H248N42O40S3
NDEQMPWY
K
3316.00
10.54
8
0
9
+7
3.84
-0.023
66.13
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.77
11
Residue Composition
number
2
A
1
R
0
N
0
D
3
C
0
E
0
Q
3
G
1
H
2
I
2
L
6
K
0
M
2
F
0
P
3
S
5
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 3 H: 1 I: 2 L: 2 K: 6 M: 0 F: 2 P: 0 S: 3 T: 5 W: 0 Y: 0 V: 1
Chemical Descriptors
31
C145H248N42O40S3
3316.00
10.54
+7
3.84
-0.023
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. epidermidis, resistant bacterial strains MRSA and VRE (anti-VRE). Also active against S. simulans (MIC 100 nM), M. flavus (MIC 75 nM), bacteriostatic, and B. megaterium (MIC 100 nM), bacteriocidal ( Wang et al., 2023 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. epidermidis, resistant bacterial strains MRSA and VRE (anti-VRE). Also active against S. simulans (MIC 100 nM), M. flavus (MIC 75 nM), bacteriostatic, and B. megaterium (MIC 100 nM), bacteriocidal ( Wang et al., 2023 ).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. epidermidis, resistant bacterial strains MRSA and VRE (anti-VRE). Also active against S. simulans (MIC 100 nM), M. flavus (MIC 75 nM), bacteriostatic, and B. megaterium (MIC 100 nM), bacteriocidal ( Wang et al., 2023 ).