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Peptide record

TPDB04459

Antibacterial Antifungal standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB04459
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ENDHRMPYELNRPNNLSKGGAKCGAAIA
Physicochemical Analysis
C126H204N42O41S2
QFTWV
AN
3027.38
8.86
5
3
9
+1
9.05
-0.975
56.07
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
1490
49.22
7
Residue Composition
number
4
A
2
R
4
N
1
D
1
C
2
E
0
Q
3
G
1
H
1
I
2
L
2
K
1
M
0
F
2
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 2 N: 4 D: 1 C: 1 E: 2 Q: 0 G: 3 H: 1 I: 1 L: 2 K: 2 M: 1 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
28
C126H204N42O41S2
3027.38
8.86
+1
9.05
-0.975
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ bacteria (L. sakei ssp. sakei JCM 1157T, L. sanfranciscensis JCM 5668, L. coryniformis ssp.coryniformis JCM 1164, L. plantarum NRIC 1067, L. animalis JCM 5670, L. pentosus JCM 1558, L. gasseri JCM 5344 , L. helveticus JCM 1554, L. lactis JCM 6123, L. lactis ssp. lactis C101910, L. lactis ssp. lactis IFO 12007 , E. faecium MR006 , E. durans MY411, C. divergens JCM 5816, W. paramesenteroides NRIC 1542, W. kandleri JCM 5817, W. halotolerans JCM 1114, and W. minor JCM 1168T). This cultu re supernatant lost its antibacterial activitycompletely after treatment with proteinase K, but main-tained antibacterial activity after autoclaving (121oC for15 min).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ bacteria (L. sakei ssp. sakei JCM 1157T, L. sanfranciscensis JCM 5668, L. coryniformis ssp.coryniformis JCM 1164, L. plantarum NRIC 1067, L. animalis JCM 5670, L. pentosus JCM 1558, L. gasseri JCM 5344 , L. helveticus JCM 1554, L. lactis JCM 6123, L. lactis ssp. lactis C101910, L. lactis ssp. lactis IFO 12007 , E. faecium MR006 , E. durans MY411, C. divergens JCM 5816, W. paramesenteroides NRIC 1542, W. kandleri JCM 5817, W. halotolerans JCM 1114, and W. minor JCM 1168T). This cultu re supernatant lost its antibacterial activitycompletely after treatment with proteinase K, but main-tained antibacterial activity after autoclaving (121oC for15 min).