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Peptide record

TPDB04455

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB04455
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept DRAVP 2.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LTTKLWSSWGYYLGKKARWNLKHPYVQF
Physicochemical Analysis
C169H244N42O38
DCEIM
LK
3472.06
10.48
6
0
13
+5
-4.10
-0.654
69.64
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
20970
603.97
9
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
1
Q
2
G
1
H
0
I
4
L
4
K
0
M
1
F
1
P
2
S
2
T
3
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 4 K: 4 M: 0 F: 1 P: 1 S: 2 T: 2 W: 3 Y: 3 V: 1
Chemical Descriptors
28
C169H244N42O38
3472.06
10.48
+5
-4.10
-0.654
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
It inhibits Gram+ bacteria. It also inhibits the flaviviruses Langat and Kunjin, coronavirus SARS-CoV-2, influenza A virus (IAV), and human immunodeficiency virus-1 (HIV-1) ( Omer et al., 2022 . In addition, downstream of Pln NC8, it is likely there is another two chain bacteriocin named plantaricin J51. Whether it is a true bacteriocin remains to be established ( Diep DB et al, 2009 ). Updated Jan2023.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
It inhibits Gram+ bacteria. It also inhibits the flaviviruses Langat and Kunjin, coronavirus SARS-CoV-2, influenza A virus (IAV), and human immunodeficiency virus-1 (HIV-1) ( Omer et al., 2022 . In addition, downstream of Pln NC8, it is likely there is another two chain bacteriocin named plantaricin J51. Whether it is a true bacteriocin remains to be established ( Diep DB et al, 2009 ). Updated Jan2023.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

It inhibits Gram+ bacteria. It also inhibits the flaviviruses Langat and Kunjin, coronavirus SARS-CoV-2, influenza A virus (IAV), and human immunodeficiency virus-1 (HIV-1) ( Omer et al., 2022 . In addition, downstream of Pln NC8, it is likely there is another two chain bacteriocin named plantaricin J51. Whether it is a true bacteriocin remains to be established ( Diep DB et al, 2009 ). Updated Jan2023.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP DRAVP 2.0

Other

It inhibits Gram+ bacteria. It also inhibits the flaviviruses Langat and Kunjin, coronavirus SARS-CoV-2, influenza A virus (IAV), and human immunodeficiency virus-1 (HIV-1) ( Omer et al., 2022 . In addition, downstream of Pln NC8, it is likely there is another two chain bacteriocin named plantaricin J51. Whether it is a true bacteriocin remains to be established ( Diep DB et al, 2009 ). Updated Jan2023.