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Peptide record

TPDB04453

Antibacterial Antifungal standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB04453
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
TPGGIDFISGGPHVAQDVLNAIKNFFK
Physicochemical Analysis
C131H200N34O37
RCEMWY
G
2843.23
7.79
3
2
11
+0
2.95
0.107
86.67
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
2
N
2
D
0
C
0
E
1
Q
4
G
1
H
3
I
1
L
2
K
0
M
3
F
2
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 2 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 3 L: 1 K: 2 M: 0 F: 3 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
27
C131H200N34O37
2843.23
7.79
+0
2.95
0.107
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.15 µM

Target

B. coagulans JCM 2257T

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
e production of other entericins such as NKR-5-3A, NKR-5-3B, and NKR-5-3C. Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATC
Evidence 2 Activity

Activity

MIC
Antibacterial
0.59 µM

Target

L. innocua ATCC 33090

Source & Reference

dbAMP DRAMP

Other

as NKR-5-3A, NKR-5-3B, and NKR-5-3C. Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei s
Evidence 3 Activity

Activity

MIC
Antibacterial
0.3 µM

Target

Enterococcus faecalis JCM 5803

Source & Reference

dbAMP DRAMP

Other

Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). N
Evidence 4 Activity

Activity

MIC
Antibacterial
1.2 µM

Target

L. plantarum ATCC 14917

Source & Reference

dbAMP DRAMP

Other

7T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). Not active: B.subtilis JCM 1465, K.rhiz
Evidence 5 Activity

Activity

MIC
Antibacterial
0.3 µM

Target

p. sakei JCM 1157T

Source & Reference

dbAMP DRAMP

Other

E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). Not active: B.subtilis JCM 1465, K.rhizophila NBRC 12708, P.pentosaceus JCM 5885, L.lact
Evidence 6 Activity

Activity

MIC
Antifungal
0.15 µM

Target

B. coagulans JCM 2257T

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
e production of other entericins such as NKR-5-3A, NKR-5-3B, and NKR-5-3C. Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATC
Evidence 7 Activity

Activity

MIC
Antifungal
0.59 µM

Target

L. innocua ATCC 33090

Source & Reference

dbAMP DRAMP Antifungipept

Other

as NKR-5-3A, NKR-5-3B, and NKR-5-3C. Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei s
Evidence 8 Activity

Activity

MIC
Antifungal
0.3 µM

Target

Enterococcus faecalis JCM 5803

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against B. coagulans JCM 2257T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). N
Evidence 9 Activity

Activity

MIC
Antifungal
1.2 µM

Target

L. plantarum ATCC 14917

Source & Reference

dbAMP DRAMP Antifungipept

Other

7T (MIC 0.15 uM), L. innocua ATCC 33090 (MIC 0.59 uM), E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). Not active: B.subtilis JCM 1465, K.rhiz
Evidence 10 Activity

Activity

MIC
Antifungal
0.3 µM

Target

p. sakei JCM 1157T

Source & Reference

dbAMP DRAMP Antifungipept

Other

E. faecalis JCM 5803 (MIC 0.3 uM), L. plantarum ATCC 14917 (MIC 1.2 uM), and Lb. sakei ssp. sakei JCM 1157T (MIC 0.3 uM). Not active: B.subtilis JCM 1465, K.rhizophila NBRC 12708, P.pentosaceus JCM 5885, L.lact