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Peptide record

TPDB04447

Antibacterial standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB04447
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 27-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
TFFRLFNRGGGKNLRIIRKGIHIIKKY
Physicochemical Analysis
C152H249N47O32
ADCEQMPSWV
I
3246.94
12.42
9
0
11
+8
2.18
-0.330
101.11
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
45.89
4
Residue Composition
number
0
A
4
R
2
N
0
D
0
C
0
E
0
Q
4
G
1
H
5
I
2
L
4
K
0
M
3
F
0
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 5 L: 2 K: 4 M: 0 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
27
C152H249N47O32
3246.94
12.42
+8
2.18
-0.330
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.25-4.0 µM

Target

S. mutans UA159 or 25175 or comD

Source & Reference

NA

Other

active against S. mutans UA159 or 25175 or comD (MIC 3.25-4.0 uM), S. gordonii (MIC 20 uM), and S. sanguinis (MIC 15 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

S. gordonii

Source & Reference

NA

Other

active against S. mutans UA159 or 25175 or comD (MIC 3.25-4.0 uM), S. gordonii (MIC 20 uM), and S. sanguinis (MIC 15 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
15 µM

Target

S. sanguinis

Source & Reference

NA

Other

against S. mutans UA159 or 25175 or comD (MIC 3.25-4.0 uM), S. gordonii (MIC 20 uM), and S. sanguinis (MIC 15 uM).