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Peptide record

TPDB04348

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB04348
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
DLTTKLWSSWGYYLGKKARWNL
Physicochemical Analysis
C128H188N32O32
CEQHIMFPV
L
2687.10
10.23
4
1
10
+3
-3.85
-0.695
75.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
19480
724.95
7
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
0
E
0
Q
2
G
0
H
0
I
4
L
3
K
0
M
0
F
0
P
2
S
2
T
3
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 4 K: 3 M: 0 F: 0 P: 0 S: 2 T: 2 W: 3 Y: 2 V: 0
Chemical Descriptors
22
C128H188N32O32
2687.10
10.23
+3
-3.85
-0.695
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020