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Peptide record

TPDB04346

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04346
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IASKFICTPGCAKTGSFNSYCC
Physicochemical Analysis
C99H153N25O30S4
RDEQHLMWV
C
2301.69
8.30
2
0
7
+2
-1.58
0.427
44.55
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1740
75.60
11
Residue Composition
number
2
A
0
R
1
N
0
D
4
C
0
E
0
Q
2
G
0
H
2
I
0
L
2
K
0
M
2
F
1
P
3
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 0 K: 2 M: 0 F: 2 P: 1 S: 3 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C99H153N25O30S4
2301.69
8.30
+2
-1.58
0.427
Evidence Records 40 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Staphylococcus aureus SG 511 or E88

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogen
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis A
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. pneumonia ATCC 6302

Source & Reference

dbAMP DRAMP

Other

e against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis A
Evidence 4 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

Streptococcus pyogenes ATCC 8668

Source & Reference

dbAMP DRAMP

Other

8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 1
Evidence 5 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. faecalis ATCC 29212

Source & Reference

dbAMP DRAMP

Other

(MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 1
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

C. xerosis ATCC 9755

Source & Reference

dbAMP DRAMP

Other

MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 o
Evidence 7 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

E.coli ATCC 11775

Source & Reference

dbAMP DRAMP

Other

(MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml),
Evidence 8 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

P.aeruginosa BC 19

Source & Reference

dbAMP DRAMP

Other

12 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128
Evidence 9 Activity

Activity

MIC
Antibacterial
0.25 µg/mL

Target

P. anaerobicus

Source & Reference

dbAMP DRAMP

Other

us 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 10 Activity

Activity

MIC
Antibacterial
0.25 µg/mL

Target

P. acnes IF 31002

Source & Reference

dbAMP DRAMP

Other

ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 11 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Staphylococcus aureus SG 511 or E88

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogen
Evidence 12 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis A
Evidence 13 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. pneumonia ATCC 6302

Source & Reference

dbAMP DRAMP Antifungipept

Other

e against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis A
Evidence 14 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

Streptococcus pyogenes ATCC 8668

Source & Reference

dbAMP DRAMP Antifungipept

Other

8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 1
Evidence 15 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. faecalis ATCC 29212

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 1
Evidence 16 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

C. xerosis ATCC 9755

Source & Reference

dbAMP DRAMP Antifungipept

Other

MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 o
Evidence 17 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

E.coli ATCC 11775

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml),
Evidence 18 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

P.aeruginosa BC 19

Source & Reference

dbAMP DRAMP Antifungipept

Other

12 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128
Evidence 19 Activity

Activity

MIC
Antifungal
0.25 µg/mL

Target

P. anaerobicus

Source & Reference

dbAMP DRAMP Antifungipept

Other

us 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 20 Activity

Activity

MIC
Antifungal
0.25 µg/mL

Target

P. acnes IF 31002

Source & Reference

dbAMP DRAMP Antifungipept

Other

ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 21 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Staphylococcus aureus SG 511 or E88

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogen
Evidence 22 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

DRAMP

Other

Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis A
Evidence 23 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

S. pneumonia ATCC 6302

Source & Reference

DRAMP

Other

e against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis A
Evidence 24 Activity

Activity

MIC
Antiparasitic
1 µg/mL

Target

Streptococcus pyogenes ATCC 8668

Source & Reference

DRAMP

Other

8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 1
Evidence 25 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

S. faecalis ATCC 29212

Source & Reference

DRAMP

Other

(MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 1
Evidence 26 Activity

Activity

MIC
Antiparasitic
1 µg/mL

Target

C. xerosis ATCC 9755

Source & Reference

DRAMP

Other

MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 o
Evidence 27 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

E.coli ATCC 11775

Source & Reference

DRAMP

Other

(MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml),
Evidence 28 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

P.aeruginosa BC 19

Source & Reference

DRAMP

Other

12 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128
Evidence 29 Activity

Activity

MIC
Antiparasitic
0.25 µg/mL

Target

P. anaerobicus

Source & Reference

DRAMP

Other

us 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 30 Activity

Activity

MIC
Antiparasitic
0.25 µg/mL

Target

P. acnes IF 31002

Source & Reference

DRAMP

Other

ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 31 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

Staphylococcus aureus SG 511 or E88

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogen
Evidence 32 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

DRAMP

Other

Active against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis A
Evidence 33 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

S. pneumonia ATCC 6302

Source & Reference

DRAMP

Other

e against S. aureus SG 511 or E88 (MIC 8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis A
Evidence 34 Activity

Activity

MIC
Antiviral
1 µg/mL

Target

Streptococcus pyogenes ATCC 8668

Source & Reference

DRAMP

Other

8 ug/ml), S. epidermidis ATCC 12228 (MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 1
Evidence 35 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

S. faecalis ATCC 29212

Source & Reference

DRAMP

Other

(MIC 4 ug/ml), S. pneumonia ATCC 6302 (MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 1
Evidence 36 Activity

Activity

MIC
Antiviral
1 µg/mL

Target

C. xerosis ATCC 9755

Source & Reference

DRAMP

Other

MIC 4 ug/ml), S. pyogenes ATCC 8668 (MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 o
Evidence 37 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

E.coli ATCC 11775

Source & Reference

DRAMP

Other

(MIC 1 ug/ml), S. faecalis ATCC 29212 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml),
Evidence 38 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

P.aeruginosa BC 19

Source & Reference

DRAMP

Other

12 (MIC 64 ug/ml), C. xerosis ATCC 9755 (MIC 1 ug/ml), E.coli ATCC 11775 (MIC 128 ug/ml), P.aeruginosa BC 19 (MIC 128 ug/ml), M. luteus 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128
Evidence 39 Activity

Activity

MIC
Antiviral
0.25 µg/mL

Target

P. anaerobicus

Source & Reference

DRAMP

Other

us 15957 or ATCC 9341 (MIC 1 or 0.25 ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).
Evidence 40 Activity

Activity

MIC
Antiviral
0.25 µg/mL

Target

P. acnes IF 31002

Source & Reference

DRAMP

Other

ug/ml), B.fragilis (Bonn) or (Koln) (MIC 128 ug/ml), P. anaerobicus (MIC 0.25 ug/ml), and P. acnes IF 31002 (MIC 0.25 ug/ml).