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Peptide record

TPDB04340

Antibacterial Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB04340
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
MGIIAGIIKVIKSLIEQFTGK
Physicochemical Analysis
C105H183N25O27S1
RNDCHPWY
I
2259.82
10.32
3
1
11
+2
1.99
0.957
148.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
3
G
0
H
6
I
1
L
3
K
1
M
1
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 6 L: 1 K: 3 M: 1 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C105H183N25O27S1
2259.82
10.32
+2
1.99
0.957
Evidence Records 2 records
Evidence 1 Activity

Activity

58% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
58% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. | J Biol Chem | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis