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Peptide record

TPDB04335

Antibacterial Antifungal Antiparasitic Antiviral Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB04335
Antibacterial Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 AI4AVP DRAMP DRAVP 2.0 ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
CLGIGSCNDFAGCGYAIVCFW
Physicochemical Analysis
C98H139N23O27S4
REQHKMPT
CG
2199.56
3.10
0
1
10
-1
-5.64
1.171
79.05
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7240
329.16
7
Residue Composition
number
2
A
0
R
1
N
1
D
4
C
0
E
0
Q
4
G
0
H
2
I
1
L
0
K
0
M
2
F
0
P
1
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 4 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 1 K: 0 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
21
C98H139N23O27S4
2199.56
3.10
-1
-5.64
1.171
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>500 µg/mL
Cytotoxic
50% Cytotoxicity | >500 | µg/mL | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Siamycins I and II, new anti-HIV peptides: I. Fermentation, isolation, biological activity and initial characterization. | J Antibiot (Tokyo) | 1995