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Peptide record

TPDB04318

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04318
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
CTFTLPGGGGVCTLTSECIC
Physicochemical Analysis
C81H132N20O28S4
ARNDQHKMWY
CGT
1962.30
3.29
0
1
5
-1
-0.25
0.940
73.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
250
12.74
9
Residue Composition
number
0
A
0
R
0
N
0
D
4
C
1
E
0
Q
4
G
0
H
1
I
2
L
0
K
0
M
1
F
1
P
1
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 4 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 1 S: 1 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C81H132N20O28S4
1962.30
3.29
-1
-0.25
0.940
Evidence Records 36 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.5
Evidence 2 Activity

Activity

MIC
Antibacterial
0.78 µg/mL

Target

Staphylococcus aureus R85

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
3.12 µg/mL

Target

Staphylococcus aureus 20424

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (
Evidence 4 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

Staphylococcus aureus 503

Source & Reference

dbAMP DRAMP

Other

209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77
Evidence 5 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Staphylococcus epidermidis 823

Source & Reference

dbAMP DRAMP

Other

s R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC66
Evidence 6 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

S. faecalis 21777

Source & Reference

dbAMP DRAMP

Other

24 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus
Evidence 7 Activity

Activity

MIC
Antibacterial
3.12 µg/mL

Target

S. pneumoniae A77

Source & Reference

dbAMP DRAMP

Other

(MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active
Evidence 8 Activity

Activity

MIC
Antibacterial
0.78 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP DRAMP

Other

3 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 9 Activity

Activity

MIC
Antibacterial
0.195 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP

Other

50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 10 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.5
Evidence 11 Activity

Activity

MIC
Antifungal
0.78 µg/mL

Target

Staphylococcus aureus R85

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MI
Evidence 12 Activity

Activity

MIC
Antifungal
3.12 µg/mL

Target

Staphylococcus aureus 20424

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (
Evidence 13 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

Staphylococcus aureus 503

Source & Reference

dbAMP DRAMP Antifungipept

Other

209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77
Evidence 14 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Staphylococcus epidermidis 823

Source & Reference

dbAMP DRAMP Antifungipept

Other

s R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC66
Evidence 15 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

S. faecalis 21777

Source & Reference

dbAMP DRAMP Antifungipept

Other

24 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus
Evidence 16 Activity

Activity

MIC
Antifungal
3.12 µg/mL

Target

S. pneumoniae A77

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active
Evidence 17 Activity

Activity

MIC
Antifungal
0.78 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP DRAMP Antifungipept

Other

3 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 18 Activity

Activity

MIC
Antifungal
0.195 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP Antifungipept

Other

50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 19 Activity

Activity

MIC
Antiparasitic
1.56 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.5
Evidence 20 Activity

Activity

MIC
Antiparasitic
0.78 µg/mL

Target

Staphylococcus aureus R85

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MI
Evidence 21 Activity

Activity

MIC
Antiparasitic
3.12 µg/mL

Target

Staphylococcus aureus 20424

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (
Evidence 22 Activity

Activity

MIC
Antiparasitic
1.56 µg/mL

Target

Staphylococcus aureus 503

Source & Reference

DRAMP

Other

209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77
Evidence 23 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Staphylococcus epidermidis 823

Source & Reference

DRAMP

Other

s R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC66
Evidence 24 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

S. faecalis 21777

Source & Reference

DRAMP

Other

24 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus
Evidence 25 Activity

Activity

MIC
Antiparasitic
3.12 µg/mL

Target

S. pneumoniae A77

Source & Reference

DRAMP

Other

(MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active
Evidence 26 Activity

Activity

MIC
Antiparasitic
0.78 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

DRAMP

Other

3 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 27 Activity

Activity

MIC
Antiparasitic
0.195 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

DRAMP

Other

50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 28 Activity

Activity

MIC
Antiviral
1.56 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.5
Evidence 29 Activity

Activity

MIC
Antiviral
0.78 µg/mL

Target

Staphylococcus aureus R85

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MI
Evidence 30 Activity

Activity

MIC
Antiviral
3.12 µg/mL

Target

Staphylococcus aureus 20424

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (
Evidence 31 Activity

Activity

MIC
Antiviral
1.56 µg/mL

Target

Staphylococcus aureus 503

Source & Reference

DRAMP

Other

209P (MIC 1.56 ug/ml), S. aureus R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77
Evidence 32 Activity

Activity

MIC
Antiviral
6.25 µg/mL

Target

Staphylococcus epidermidis 823

Source & Reference

DRAMP

Other

s R85 (MIC 0.78 ug/ml), S. aureus 20424 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC66
Evidence 33 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

S. faecalis 21777

Source & Reference

DRAMP

Other

24 (MIC 3.12 ug/ml), S. aureus 503 (MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus
Evidence 34 Activity

Activity

MIC
Antiviral
3.12 µg/mL

Target

S. pneumoniae A77

Source & Reference

DRAMP

Other

(MIC 1.56 ug/ml), S. epidermidis 823 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active
Evidence 35 Activity

Activity

MIC
Antiviral
0.78 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

DRAMP

Other

3 (MIC 6.25 ug/ml), S. faecalis 21777 (MIC 50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.
Evidence 36 Activity

Activity

MIC
Antiviral
0.195 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

DRAMP

Other

50 ug/ml), S. pneumoniae A77 (MIC 3.12 ug/ml), B. subtilis ATCC6633 (MIC 0.78 ug/ml) and M. luteus ATCC 9341 (MIC 0.195 ug/ml). Active against MRSA, VRE, C. difficile.