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Peptide record

TPDB04308

Antibacterial Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB04308
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
AWNTYDYMKREHSLVKPYQG
Physicochemical Analysis
C113H164N30O32S1
CIF
Y
2486.79
9.39
4
2
8
+1
3.17
-1.305
39.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
9970
400.92
7
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
1
E
1
Q
1
G
1
H
0
I
1
L
2
K
1
M
0
F
1
P
1
S
1
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 0 L: 1 K: 2 M: 1 F: 0 P: 1 S: 1 T: 1 W: 1 Y: 3 V: 1
Chemical Descriptors
20
C113H164N30O32S1
2486.79
9.39
+1
3.17
-1.305
Evidence Records 9 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
5% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 2 Activity

Activity

9% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
9% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 3 Activity

Activity

15% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
15% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 4 Activity

Activity

20% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
20% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 5 Activity

Activity

25% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
25% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 6 Activity

Activity

29% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
29% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 7 Activity

Activity

34% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
34% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 8 Activity

Activity

37% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
37% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrobrachium rosenbergii mannose binding lectin: Synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis. | Fish Shellfish Immunol | 2015
Evidence 9 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis