Back to search

Peptide record

TPDB04301

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04301
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LYKRYILRKFKFLKKKLKKK
Physicochemical Analysis
C132H225N35O23
ANDCEQGHMPSTWV
K
2670.46
11.38
11
0
9
+11
3.84
-1.070
97.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
111.59
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
9
K
0
M
2
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 9 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
20
C132H225N35O23
2670.46
11.38
+11
3.84
-1.070
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>640 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >640 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Two optimized antimicrobial peptides with therapeutic potential for clinical antibiotic-resistant Staphylococcus aureus. | Eur J Med Chem | 2019
Evidence 2 Activity

Activity

25% Killing
Toxicity
640 µg/mL
Cytotoxic
25% Killing | 640 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Two optimized antimicrobial peptides with therapeutic potential for clinical antibiotic-resistant Staphylococcus aureus. | Eur J Med Chem | 2019