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Peptide record

TPDB04298

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB04298
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
SVPTSVYTLGIKILWSAYKH
Physicochemical Analysis
C108H167N25O28
RNDCEQMF
S
2263.66
9.97
3
0
10
+2
-1.43
0.325
112.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
8480
374.61
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
2
K
0
M
0
F
1
P
3
S
2
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 2 M: 0 F: 0 P: 1 S: 3 T: 2 W: 1 Y: 2 V: 2
Chemical Descriptors
20
C108H167N25O28
2263.66
9.97
+2
-1.43
0.325
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020