Back to search

Peptide record

TPDB04291

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04291
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SSGWVCTLTIECGTVICAC
Physicochemical Analysis
C81H132N20O27S4
RNDQHKMFPY
C
1946.30
3.29
0
1
7
-1
-1.30
1.268
97.37
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5750
295.43
9
Residue Composition
number
1
A
0
R
0
N
0
D
4
C
1
E
0
Q
2
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
2
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 4 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
19
C81H132N20O27S4
1946.30
3.29
-1
-1.30
1.268
Evidence Records 28 records
Evidence 1 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Staphylococcus aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L56
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Streptococcus pyogenes SKF13400

Source & Reference

dbAMP

Other

ive against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. pneumoniae L44

Source & Reference

dbAMP

Other

P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml),
Evidence 4 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

E.faecium VanS L568

Source & Reference

dbAMP

Other

(MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), a
Evidence 5 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

Enterococcus faecalis VanS L559 or VanA L560

Source & Reference

dbAMP

Other

400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active a
Evidence 6 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

, E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. d
Evidence 7 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

C.albicans ATCC 90028

Source & Reference

dbAMP

Other

.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. difficile.
Evidence 8 Activity

Activity

MIC
Antifungal
32-64 µg/mL

Target

Staphylococcus aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L56
Evidence 9 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Streptococcus pyogenes SKF13400

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ive against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L
Evidence 10 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. pneumoniae L44

Source & Reference

dbAMP CAFPdb Antifungipept

Other

P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml),
Evidence 11 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

E.faecium VanS L568

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), a
Evidence 12 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

Enterococcus faecalis VanS L559 or VanA L560

Source & Reference

dbAMP CAFPdb Antifungipept

Other

400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active a
Evidence 13 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. d
Evidence 14 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

C.albicans ATCC 90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. difficile.
Evidence 15 Activity

Activity

MIC
Antiparasitic
32-64 µg/mL

Target

Staphylococcus aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400

Source & Reference

NA

Other

active against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L56
Evidence 16 Activity

Activity

MIC
Antiparasitic
2 µg/mL

Target

Streptococcus pyogenes SKF13400

Source & Reference

NA

Other

ive against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L
Evidence 17 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

S. pneumoniae L44

Source & Reference

NA

Other

P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml),
Evidence 18 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

E.faecium VanS L568

Source & Reference

NA

Other

(MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), a
Evidence 19 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

Enterococcus faecalis VanS L559 or VanA L560

Source & Reference

NA

Other

400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active a
Evidence 20 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

, E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. d
Evidence 21 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

C.albicans ATCC 90028

Source & Reference

NA

Other

.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. difficile.
Evidence 22 Activity

Activity

MIC
Antiviral
32-64 µg/mL

Target

Staphylococcus aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400

Source & Reference

NA

Other

active against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L56
Evidence 23 Activity

Activity

MIC
Antiviral
2 µg/mL

Target

Streptococcus pyogenes SKF13400

Source & Reference

NA

Other

ive against S. aureus MetS ATCC 6538P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L
Evidence 24 Activity

Activity

MIC
Antiviral
16 µg/mL

Target

S. pneumoniae L44

Source & Reference

NA

Other

P or MetS ATCC 19636 or MetR L1400 (MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml),
Evidence 25 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

E.faecium VanS L568

Source & Reference

NA

Other

(MIC 32-64 ug/ml), S. pyogenes SKF13400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), a
Evidence 26 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

Enterococcus faecalis VanS L559 or VanA L560

Source & Reference

NA

Other

400 (MIC 2 ug/ml), S. pneumoniae L44 (MIC 16 ug/ml), E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active a
Evidence 27 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

, E.faecium VanS L568 (MIC 128 ug/ml), E.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. d
Evidence 28 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

C.albicans ATCC 90028

Source & Reference

NA

Other

.faecalis VanS L559 or VanA L560 (MIC 128 ug/ml), E.coli ATCC 25922 (MIC >128 ug/ml), and C.albicans ATCC 90028 (MIC >128 ug/ml). Active against MRSA, VRE (anti-VRE) and C. difficile.