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Peptide record

TPDB04252

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB04252
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifp Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPIALKALGSIFPKIL
Physicochemical Analysis
C93H153N19O19
RNDCEQHMTWYV
L
1841.35
10.60
2
0
11
+2
-2.75
1.512
172.35
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
2
K
0
M
2
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 2 M: 0 F: 2 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C93H153N19O19
1841.35
10.60
+2
-2.75
1.512
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 3 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 4 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 5 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 6 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 7 Activity

Activity

MIC
Antiviral
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 8 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 50 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
>200 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Isolation, characterization and molecular cloning of new antimicrobial peptides belonging to the brevinin-1 and temporin families from the skin of Hylarana latouchii (Anura: Ranidae). | Biochimie | 2009
Evidence 10 Activity

Activity

LD50
Toxicity
200 µg/mL
Hemolytic
Hemolytic_activity: [Ref:19340924]LD50>200 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2009 Apr 91(4):540-547.