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Peptide record

TPDB04240

Antibacterial Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB04240
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GATAIKQVKKLWKKKGG
Physicochemical Analysis
C85H149N25O20
RNDCEHMFPSY
K
1841.27
11.21
6
0
6
+6
3.70
-0.800
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
298.71
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
1
L
6
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 1 K: 6 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
17
C85H149N25O20
1841.27
11.21
+6
3.70
-0.800
Evidence Records 4 records
Evidence 1 Activity

Activity

16% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
16% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
20% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 3 Activity

Activity

27% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
27% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis