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Peptide record

TPDB04238

Antibacterial Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB04238
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GATAIKQVKKLFKKKGG
Physicochemical Analysis
C83H148N24O20
RNDCEHMPSWY
K
1802.24
11.21
6
0
6
+6
4.42
-0.582
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
1
L
6
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 1 K: 6 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C83H148N24O20
1802.24
11.21
+6
4.42
-0.582
Evidence Records 7 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
0% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 2 Activity

Activity

18% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
18% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 3 Activity

Activity

20% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
20% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 4 Activity

Activity

30% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
30% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 5 Activity

Activity

20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
50% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | Chem Biol Drug Des | 2011
Evidence 7 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis