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Peptide record

TPDB04224

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB04224
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIIKVIKSLIEQFTGK
Physicochemical Analysis
C83H144N20O22
ARNDCHMPWY
I
1774.18
10.32
3
1
7
+2
3.00
0.487
140.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
1
Q
2
G
0
H
4
I
1
L
3
K
0
M
1
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 4 L: 1 K: 3 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C83H144N20O22
1774.18
10.32
+2
3.00
0.487
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. | J Biol Chem | 2012
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.22371493]Non-hemolytic at 10µg/mL against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2012 Apr 20 287(17):13889-98.