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Peptide record

TPDB04223

Antibacterial Antifungal Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB04223
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLRRLLRRLLRRLLRR
Physicochemical Analysis
C96H186N40O17
ANDCEQGHIKMFPSTWYV
RL
2172.79
13.25
8
0
8
+8
2.00
-0.350
195.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C96H186N40O17
2172.79
13.25
+8
2.00
-0.350
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
12 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 12 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthetic cationic amphiphilic ?-helical peptides as antimicrobial agents. | Biomaterials | 2011
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis