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Peptide record

TPDB04219

Antibacterial Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB04219
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KKYLLPIVGNLLKSLL
Physicochemical Analysis
C88H154N20O20
ARDCEQHMFTW
L
1812.31
10.46
3
0
9
+3
-0.56
0.762
188.75
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
82.22
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
6
L
3
K
0
M
0
F
1
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 6 K: 3 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
16
C88H154N20O20
1812.31
10.46
+3
-0.56
0.762
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
58.52 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 58.52 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine model. | BMC Immunol | 2012
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis