Back to search

Peptide record

TPDB04209

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04209
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GRKSAKKIGKRAKRI
Physicochemical Analysis
C73H141N29O17
NDCEQHLMFPTWYV
K
1697.11
12.72
8
0
4
+8
6.57
-1.467
65.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
0
L
5
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 0 K: 5 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C73H141N29O17
1697.11
12.72
+8
6.57
-1.467
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
7727 µg/mL
Cytotoxic
50% Cell death | 7727 | µg/mL | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
The ATPase activity of the mycobacterial plasma membrane is inhibited by the LL37-analogous peptide LLAP. | Peptides | 2015
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The ATPase activity of the mycobacterial plasma membrane is inhibited by the LL37-analogous peptide LLAP. | Peptides | 2015