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Peptide record

TPDB04207

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB04207
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FRKSKEKIGKEFKRI
Physicochemical Analysis
C87H148N26O21
ANDCQHLMPTWYV
K
1894.29
11.08
7
2
4
+5
7.87
-1.473
52.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
2
E
0
Q
1
G
0
H
2
I
0
L
5
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 1 H: 0 I: 2 L: 0 K: 5 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C87H148N26O21
1894.29
11.08
+5
7.87
-1.473
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
11226 µg/mL
Cytotoxic
50% Cell death | 11226 | µg/mL | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
The ATPase activity of the mycobacterial plasma membrane is inhibited by the LL37-analogous peptide LLAP. | Peptides | 2015
Evidence 2 Activity

Activity

4% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The ATPase activity of the mycobacterial plasma membrane is inhibited by the LL37-analogous peptide LLAP. | Peptides | 2015